The COVID-19 crisis is confronting society with huge challenges. Governments all over the world are focusing on the complex task of setting up rapid high-volume vaccination campaigns so that life can get back to normal as soon as possible. In consonance with these efforts, blockchain technology can help tackle several of the challenges imposed by COVID-19, and it can even help our economy recover more quickly from this pandemic. Professor Kristof Stouthuysen and researcher Tineke Distelmans talk about the possible applications of blockchain in vaccine tracking and storage, a COVID-19 passport and the global organisation of supply chains.